IRED - Imine-reducing enzymes

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IRED database completion

Paper search score
10%
'Thorough' search carried out more than 2 years ago by William Finnigan
Data entry completion
39%
34 out of 86
Priority papers completed
83%
5 out of 6

IRED curation team

(20) * William Finnigan - University of Manchester

(2) * yuqi yu - University of Manchester

(2) Rachel Heath - University of Manchester

(1) Tom Thorpe - University of Manchester

(1) Tom Lister - UoM

* indicates team admin
( ) shows number of papers curated

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IRED database statistics

735 enzyme records, 532 with protein sequences

20675 UniRef50 homologues

5899 activity records - 55 % active , 44 % inactive

911 unique product molecules

Reactions by IRED

Imine reduction

Featured in 16 IRED papers

Cofactor usage: NADPH --> NADP

Reductive amination

Featured in 15 IRED papers

Multi-step

Cofactor usage: NADPH --> NADP

Ketone amination

Featured in 6 IRED papers

Cofactor usage: NADPH, NH3 --> NADP

Amine oxidation

Featured in 2 IRED papers

Cofactor usage: NADP+ --> NADPH

Iminium reduction

Featured in 2 IRED papers

Cofactor usage: NADPH --> NADP

Amine deracemization or kinetic resolution

Featured in 1 IRED papers

Multi-step

Cofactor usage: NADP+, Reducing agent --> NADPH

Aldehyde amination

Featured in 0 IRED papers

Cofactor usage: NADPH, NH3 --> NADP

Conjugate reduction eneimine

Featured in 0 IRED papers

Cofactor usage: NADPH --> NADP+, H2O