IRED - Imine-reducing enzymes

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IRED database completion

Paper search score
80%
'Thorough' search carried out in the last year by William Finnigan
Data entry completion
30%
24 out of 80
Priority papers completed
60%
3 out of 5

IRED curation team

(17) * William Finnigan - University of Manchester

(3) * yuqi yu - University of Manchester

(2) Rachel Heath - University of Manchester

(1) Tom Thorpe - University of Manchester

(1) Tom Lister - UoM

* indicates team admin
( ) shows number of papers curated

IRED database statistics

722 enzyme records, 519 with protein sequences

12276 UniRef50 homologues

5370 activity records - 54 % active , 45 % inactive

878 unique product molecules

Reactions by IRED

Imine reduction

Featured in 12 IRED papers

Cofactor usage: NADPH --> NADP

Reductive amination

Featured in 12 IRED papers

Multi-step

Cofactor usage: NADPH --> NADP

Ketone amination

Featured in 6 IRED papers

Cofactor usage: NADPH, NH3 --> NADP

Iminium reduction

Featured in 2 IRED papers

Cofactor usage: NADPH --> NADP

Amine oxidation

Featured in 1 IRED papers

Cofactor usage: NADP+ --> NADPH

Amine deracemization

Featured in 1 IRED papers

Multi-step

Cofactor usage: NADPH, Reducing agent --> NADP+

Aldehyde amination

Featured in 0 IRED papers

Cofactor usage: NADPH, NH3 --> NADP

Conjugate reduction eneimine

Featured in 0 IRED papers

Cofactor usage: NADPH --> NADP+, H2O